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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb4b171eec3377d8e6dd09f4237b1a1592075585513989f25f404b25c3a069ed' 
  AND token = 'bETXXYMi0tmS3cc+leb4dG0mqkIkbm+04cK72t8I9Fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}