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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57beeec7269dac469537b608f172d4bfc7bf3e898796541488c19077273e71d4' 
  AND token = '+yBMAlINaEUNa/A4NZ3HR8H4pmnFs5hJmODuTG/RVfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}