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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '594ec558dbd526b46c72f81e872b9f18f2e6c41e9a039ebbc6880ed22a702c48' 
  AND token = 'V6ZHxCoouop9PyVX4E07+uoU0IJTjwrp3UIk7/qwlZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}