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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc65a6b629238485ed1439986be5a94df3bf9d6f5306d96c5c8a38a63d0a5f81' 
  AND token = 'iz37fNMN3spdTG7+2keifKJ0zRh3M8lIvfuOXWrKDL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}