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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d8c1689bd558c34103bcc157404a66521915a2e3ea12b31e3cf98c3c59ae454' 
  AND token = 'iMfqTLRqwWZCgcST2SbYWRKz1SJu6l8zDvKoWnpRSfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}