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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19aab1a2ffe18b4a7386da41c90d7842035ef3f45497dda41b575f7981b91a43' 
  AND token = '2KRRXEr2kOLutKB+uXMtZdcEqg4LOXsPSuZvGmR7YB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}