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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185dbdf127cfa8f9bc46b4dc8bb66085887db50c2df702bdeb67830812e55489' 
  AND token = 'M2ZUwjOFEX26pcl6ZDp+G4DMG9TQ6uGA+kIry5noyVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}