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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de127c5f2bfad8f837c861da962b89aa49502132264272a749ec95b86747efc2' 
  AND token = 'VhbrKXoF5aDVbmuy1IfGtXlPx2kXF+5H4tzMZ4zMVTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}