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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '827ae6c1f1cc733a2e2b9d311d14cbbbd8f804404f2b38d0ae7cbd4efd227726' 
  AND token = '4uK0wRufS8gdSL7m44LsJpzMlyZmDTHeP9o6cdvLkzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}