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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c57160c64fe3f339d6905e36e3f4beb6c846c16cfa15711c55f0017405f04d' 
  AND token = 'e5IaD4R86In7+VedAyQtPts9HCLYpUF/ll9w4EWXSbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}