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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d48d0357651c3c3de942476118f60f5e794383184209c0fd05a4861e02c27d5' 
  AND token = 'YMeXHZIv6UTsZ1JKrDoUABqemf2ftyHVa48QzIuF1X0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}