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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '642ffec1e43f2bea24d5496c2848c2b86ff141ae1af74e222ad71b8ab3f5d153' 
  AND token = 'pZGOXp5UdRocLsLTirpuxd+H54CdA3MrMRMJ42fvIPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}