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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c7c47813d74ed6113c4f5c8e143b9d7d73b3a2bd86cf9274558ebb414dc18f8' 
  AND token = '1yM2Mys8u9Hv08LAMPVeNP+9plgsp+8aVbw22Xgx7Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}