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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7afdfbba5e7f52c9d09f8d6d01b4508063e2c12d311fb8f71370f764a3df61' 
  AND token = 'tEcslVdkL5aNdTrrR9e9w45jvpiLCcAwKeSL7OcXiPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}