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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '948b1fba29bb4d239a4c25afeab1af83916717c7531ef4482cbfc179a49356f6' 
  AND token = 'oH7uM3lLvAwyKfsBwECVG8sbLAIA1A3NlDzFVQ9/SRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}