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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '744eeefc7549f7e87e80e363dca75ff5d5b551825738faa04288e5c6c6b52ec2' 
  AND token = 'YEXS+kapBL6lF/aUZFZtoi6BkQfl1k7mA/8ThfzZdIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}