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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7f6da5bd138f8ba23af5cecfaced2a38220a5aab286f4ab5b139f2fc2c02a6' 
  AND token = '+ygp7icioeRtCnv9Irheg2A9f8kNI5yKObm19KgInK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}