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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e593ea66b05332430633f4a5164190c9c6bf80953c1a8a2b8404d7638b366cf' 
  AND token = 'C6wzW7pDCvLzwr+IPTk7dEX8YDUr9YbZJ0c5DfOH9a0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}