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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49eb7ef9a7465d4116b2fac378a891e9926893e4b0a7ef33b26856c49aca2455' 
  AND token = 'ih6VNoLcJzfe9BTD2oiNeo7iKB7ht706xhluPrzzc5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}