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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44eafe61bc5fc54bcb1b1f6cedcec43af5da8990d88791d2cbca1d53dcd2e77a' 
  AND token = 'W3uzCfepLS0/QfQE9DlNRb/26cGhDsQInBzZyjEnmF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}