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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9971fb98f2f79d77a8bac3c1df39918fb4909b423c84fbe3483a6c2f698da4c' 
  AND token = 'AfaVKYAuIQyXik/d18Y+HUAAcLEifOAS8ZRSdh1Q4D8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}