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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54b784e475b5069c80727f54a6cfecdade4cfb99dfaf5eecdaed63e9b41b7846' 
  AND token = 'yirrhi9utu6vw2gzQre1ra4Oj5GAjPCUCQ7vEwUBfhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}