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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f57a24a859f16262206e811e0a67b974e0bf37e53abad9a3b6b8f255d4fbe785' 
  AND token = 'ZuwczMJWymUgcVQ46fFKafP8SmMd/0hb+aOxaWm62y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}