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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e9c0d2f4cb629e1bc431c84eaa4bd3fe0204225e8acc55c874264603e546b71' 
  AND token = 'KiYoH2/IzFOSvBaF0hPl1+dElkWGUFuC5mZIbT67nCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}