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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a89c0c6d875c6151810c22873e7cdb63f46f71c4a6a0904ff547066d719f7e0b' 
  AND token = 'qDv5Hg98VsjOCDnROM03UVkf1ilI/KZuxrXOapbdgpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}