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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e3f3cff1c21601ed91b60c737aaa7e1d9903a10048a0c4c9bdd948f949dfb63' 
  AND token = '2SodNx1MXpAKArC5qRAzYj6fLHNDwxKzv/e2YGN0sYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}