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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28890b42b7c6bae8b407d0286493d7793db7f5dfa1d2fcd6448a6edca8e33834' 
  AND token = 'npzQuCk2TUkov3MzbQ66p7jAnsusrNGE3QdfAm+tW+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}