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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fdb0744a4a588737aed8e22c202c076564ea4b7e79280378964980f35e077fa' 
  AND token = 'eNTF1+K2aAiVO1VjHrvXaIb5SAb74c1Uiv0RBkOvmpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}