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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b63a533bf3c8246322e05a7a761a603b01058db91a387172e03639de2f16759' 
  AND token = 'WmPYBw6dJUBTVdPA1XJXgvZrrcnLYFLnU+lTEgPYT2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}