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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6188a841f7c93008b6a9942985badb70554db2528828e85b9eb6d7d58531f07e' 
  AND token = 'oXoLSu+uT7DYZzMxlUXVbBkeYqrAHtBS8DWds9zHhEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}