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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33dee5350015b901962d6f5e9748c64b3ec30daca90f103ba3f0213dd0e00fd9' 
  AND token = 'Cd02MscMBYPPw8n9LtiTWNt2eZFX3sRxtb0pkz4wjpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}