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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50de89e82e959c93a4fa4a27319d97048d4f45469cfe4d9302dc16c7969740b2' 
  AND token = 'mPsKySt/3+G8HTVg89DVWBo0A+rstPabkvvCKMaZmKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}