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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '399c63f93447895a61de5b469e26c18e57a9269873b0b94962f9c2522027b3b7' 
  AND token = 'gpSMsyF02LoSSmtdInR5UacnpYze7wQ4eZzkSz8P6ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}