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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8879a0fdc73a4b73e202b32f6f2e9176f0749f8c7365415d88e30ec108f96d' 
  AND token = 'a+w3yBZoOeKQnCE8OKCdDH0/xGJlRQOdJz+r4cyu94c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}