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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac57bfd133f4809895444a2c5f2b0ea998b220237deefb7ef5d274f156ee9a17' 
  AND token = 'nMZ7umtZnxm9V84j8W3WsiLouDtA8oJt5HGyzZFGNj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}