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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e94e6101c9e19c9da0c7989d970ddf1f6d4341b2c303532b3a0bde0979c529a6' 
  AND token = 'mdxZ5AjqyTNh2PrZ3UEFod7qWUOrbImL8ZmdinIbi7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}