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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17e0a58688cbdc41d7023b00b5be4aab4501d749fdc43ed6b947f7b8ea2c2d4b' 
  AND token = 'nezaDrQItbS/xnKCpDY0IeLNzhktj71++W/BQxeRXrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}