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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbca6411124813e12352a3fe06c82d70b66fde0e755a54d0eedac077174204a4' 
  AND token = 'CgV0Nje8ZYbhvldsg7wefpfz55eBLsaqFqbucQcdWUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}