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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c2e0a60ac6b9cc979434e1f60dd645f12f570758f3dcec1ce7ed6536d5c0e41' 
  AND token = 'C5ufG+GfY52a3ZqND4G9zO08ddoaBdvhkYOs8ogwFys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}