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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73066428ba1e60eda65665b43c574278a1f5edc63713136c862b96411e7fd217' 
  AND token = 'N4N+b+gORGV/aM3o+H+lHpXOdFvGMyM4SPNIN2LQvGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}