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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc850564d3a5982159c539c95d04ebab3f0c1c1696be2f72cf9724dda919c54' 
  AND token = 'KY14yTE/1pZ8zJqMuKSR2ul30OiEGK81xiCldl1o51o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}