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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd608d787eb3b87df7cf62a2546a5f328a594a0d0a926ec6d5dec47fa8d297965' 
  AND token = 'fWt/wk+APZQ3f8WOzIVO8UJCQgUR06EDumlQJXOx8AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}