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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac5f512b3fd7d10ce71f11311afeb20a8a917f24b99d003e26441947f2913106' 
  AND token = 'RC/yXOnt2OAJrPfTC62WnaMYDyMGJioZxLatzlspJ2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}