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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fb734dec6c9f29398e219073ee478b49848d8a4f39fe914e0027e770a7927ff' 
  AND token = 'UfgulurlAFJpo+rlEjpagrxxZd1A6akEQ4KlJoU3heA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}