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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cd0d21a9de13460acb79875d49c54a890ba35a0fb27d1c1a0ecbd39f36b28de' 
  AND token = 'AJFCiALCRmACZV+F4JoVMLVBFc+4I3prFGjJlJQqrLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}