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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f994382695afa570edb7b15c6acfe069d0d66bea37b691b82e497d49d09fb1e4' 
  AND token = 'NULPA8f1EM6uvbfpaF2Dg6JWvYI+pTiM5huKH3D3Bng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}