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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c657dc2c3b286b129b285225a921b879bd2b12e98179724a7abd24eab3ef40' 
  AND token = 'TwI2xbFzHCQtS8Amzx5JpjsWnFU/aqNvVa/4LaacPAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}