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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4e4684383b617d8b6be7636bdd8874b880d876de75d0235367a42c72edc3da6' 
  AND token = 'daSY/GnchKOwqgHacKNfC7Z07GGRXiazS2TYc3XXyAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}