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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dc2f2e6d6edae0ce3e405e73a5c02450ef32f6085567cdac35cc6ab85f27fd4' 
  AND token = 'ZYtyxn5a28/TloXCUdwdKrT0Ye3fYKFtVx7RJupFjdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}