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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821ba8a5fdb1e9183962b6c91b990d3ff09ab26711730c9611a444436b24c4c1' 
  AND token = 'LddZbhhAn/F6/JNgEnlYFabJGbIq0flZdXc2JxHAMHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}